Joe Biden has currently received more votes than any presidential candidate in US history.
The 77-year-old, who once called himself the “poorest man in Congress”, has made an incredibly successful political career for himself.
But Joe Biden has had a particularly tough journey to get to where he is today.
When he was just embarking on his journey in politics in 1973 his life was changed forever.
Just weeks after Biden was elected as US Senator for Delaware, he received a phone call telling him his wife Neilia and his 13-month-old daughter Naomi had been killed in a car accident.
He was also told that his sons Hunter, four, and Beau, three, were in critical condition.
Biden explained what it was like to receive the phone call in a speech at Yale in 2015.
He said: “Six weeks after my election, my whole world was altered forever.
“While I was in Washington hiring staff, I got a phone call. My wife and three children were Christmas shopping, a tractor trailer broadsided them and killed my wife and killed my daughter.
“And they weren’t sure that my sons would live.”
Beau and Hunter escaped with multiple broken bones and fractures.
Another tragedy hit his family in 2015, when Beau, who was in the car crash, died of a brain tumour.
Beau served as Attorney General of Delaware for two terms until 2014.
In 2010 he visited hospital with symptoms including headaches, numbness and paralysis.
Doctors diagnosed him with “mild stroke”, according to officials, but his symptoms became worse over the next three years.
He was diagnosed with brain cancer in 2013, received radiation and chemotherapy, and was stable.
But in May 2015 he went back into hospital after a relapse, and died 10 days later.
In his 2017 book called Promise Me, Dad, he wrote that “the pain… seemed unbearable in the beginning, and it took me a long time to heal, but I did survive the punishing ordeal.
“I made it through, with a lot of support, and reconstructed my life and my family.”
Biden married his current wife Jill in 1977.
He has described how his experiences have helped him connect with voters who have been through similar tragedy.
In an interview with MSNBC, he said: “You’d be amazed at the number of people who come up to me. I mean hundreds of people over time. They’ll throw their arms around me, men and women, and say, ‘I just lost my son, I just lost my father, I just lost my wife.’ And all they want to know is that you’re going to make it.”