Mouthwash can kill coronavirus in 30 seconds, scientific study finds

Mouthwash can eradicate the coronavirus in a laboratory within 30 seconds of exposure, according to a scientific study.

The preliminary result comes in a clinical trial investigating whether the use of over-the-counter mouthwash has the potential to lower the levels of Covid-19 in a patient’s saliva.

The Cardiff University report said mouthwashes containing at least 0.07% cetypyridinium chloride (CPC) showed “promising signs” of fighting the virus.

The report – The Virucidal Efficacy of Oral Rinse Components Against SARS-CoV-2 In Vitro – has yet to be peer reviewed, but supports another study published last week that found CPC-based mouthwashes to be effective in reducing the viral load of Covid.

The latest test was conducted by scientists in the university lab and mimicked the conditions of a person’s naso / oropharyngeal passage using mouthwash brands, including Dentyl.

A clinical trial will then investigate the effectiveness of mouthwash in reducing the viral load in the saliva of Covid-19 patients at the University Hospital of Wales in Cardiff, the results of which will be published in the first half of 2021.



Dentyl is the only UK mouthwash brand participating in the 12-week clinical trial led by Professor David Thomas of Cardiff University entitled “The Measurement of Mouthwash Antiviral Activity Against Covid-19”.

Dr. Thomas told the PA news agency, “While these mouthwashes are very effective in eradicating the virus in the lab, we need to see if they work in patients and this is the point of our ongoing clinical study.

“It is important to point out that the study will not provide us with direct evidence of viral transmission between patients, which would require a different type of study on a much larger scale.

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“However, the ongoing clinical trial will show us how long the effects last after a single administration of the mouthwash in patients with Covid-19.”

He added: “While this in vitro study is very encouraging and a positive step, clearly more clinical research is now needed.

“We need to understand whether the effect of over-the-counter mouthwashes on the Covid-19 virus achieved in the lab can be reproduced in patients, and we look forward to completing our clinical trial in early 2021.”

Dr. Nick Claydon, a specialist periodontist, said he found the study “very valuable.”

He said: “ If these positive results are reflected in the Cardiff University clinical trial, CPC-based mouthwashes such as Dentyl used in the in vitro study could become an important addition to people’s routine, along with the washing hands, taking physical distance and wearing masks, both now and in the future. “

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