New research shows the extent of damage caused by vaping, as experts say it damages major organs just like cigarettes.
The popular devices can cause cardiovascular disease by triggering the hardening of arteries, say researchers.
Other fatal illnesses triggered by vapes as well as shisha pipes include inflammation and DNA damage, which could also cause cancer.
Scientists have warned vaping can reduce resistance to coronavirus and make death more likely.
In the first study of its kind, researchers compared the effects of three types of smoking and found all have cause injury to vital organs, reports Daily Record.
The German team urged smokers to try to give up the habit – no matter which method they prefer.
It echoes calls from the World Health Organisation, the US Centres for Disease Control and Prevention, the Food and Drug Administration and the European Society of Cardiology.
Author Professor Thomas Munzel, a cardiologist at the University Medical Centre Mainz, said: “All three forms of smoking and vaping lead to increased production of free radicals in blood vessel tissue, such as superoxide.
“This breaks down nitric oxide, which protects against inflammation and clogging of the arteries.”
Munzel said “misconceptions” e-cigs and water pipes are substantially less harmful have fuelled their popularity.
Countless flavours and the lack of regulations make them an attractive gateway drug for adults and adolescents who have not previously smoked.
There are now more than 3.6million vapers in the UK. Munzel and colleagues found tobacco cigarettes, water pipes and e-cigs increased stiffness of the arteries by 10, nine and seven per cent respectively.
Results also showed water pipes and e-cigs more than tripled and almost doubled the risk of chronic obstructive pulmonary disease, respectively.
Cases rose eightfold among traditional smokers.
Lung cancer rates soared twelvefold among the latter – and more than doubled in the water pipe smokers.
Evidence for vapers was inconclusive.