A woman using migraine medication managed to trigger a rare reaction in her body that led to her feeling a burning sensation in her legs, a new report has revealed.
Doctors diagnosed the woman with a now unusual condition, which had numerous outbreaks during the middle ages.
The 24-year-old woman first went to medical staff when she started to feel a burning sensation in her legs – from her thigh all the way down to her toes.
She also suffered discolouration in her feet and had trouble walking with both legs being cold to the touch.
A study of the woman published in the New England Journal of Medicine revealed her symptoms.
It said: “A 24-year-old woman who had been receiving antiretroviral therapy presented with severe, burning pain in the legs after taking ergotamine for a migraine headache.
“CT angiography revealed diffuse, symmetric narrowing of the arteries in both legs, a finding consistent with ergotism.”
Her symptoms first started when she started to take medication called ergotamine for severe headaches and, as she was born with HIV, was also taking several other antiviral drugs at the same time.
Based on her symptoms, doctors determined she suffered from ergotism, which had normally been caused by ingesting poisonous compounds made by a fungus that infects cereal grains.
Known as St Anthony’s fire, the bizarre outbreaks would be caused by a natural chemical and struck down many in Europe.
Ergotism had been practically eliminated in the 1800s with the removal of infected grains from the harvest taking place more frequently.
Today, it is caused by medications that might have too high a dose or prolonged period of treatment.
Unusual conditions reveal themselves to be more common than first believed with numerous people reporting their rare afflictions.
A woman with a rare condition was left in a persistent state of arousal – but the sensation was so painful that she couldn’t have sex for months.
Lior Ofir Schwartz started experiencing genital pain, which was triggered even when she wasn’t being stimulated sexually.
This discomfort worsens when she’s stressed and also flares up in the evening.
Lior explained: “In days that I experience extreme stress I feel the need to put pressure in my clitoral region as it feels painful.
“I usually feel this in times of stress and usually at night before bed.
“The feeling is a painful arousal; it feels like a tingling in your genital region that all you want to do is put pressure on it or masturbate to relieve the pain.”